- 產(chǎn)品描述
腺病毒IgA、IgG免疫診斷試劑盒
廣州健侖生物科技有限公司
(廣州健侖生物科技有限公司是集研制開發(fā)、銷售、服務(wù)于一體的優(yōu)良企業(yè),公司產(chǎn)品涉及臨床快速診斷試劑、食品安全檢測試劑,違禁品快速檢測,動(dòng)物疾病防疫檢測試劑,免疫診斷試劑、臨床血液學(xué)和體液學(xué)檢驗(yàn)試劑、微生物檢驗(yàn)試劑、分子生物學(xué)檢驗(yàn)試劑、臨床生化試劑、有機(jī)試劑等眾多領(lǐng)域,同時(shí)核心代理Panbio、FOCUS、Qiagen、IBL、CORTEZ、Fuller、Inbios、BinaxNOW、LumuQuick、日本富士、日本生研等多家有名診斷產(chǎn)品集團(tuán)公司產(chǎn)品,致力于為商檢單位、疾病預(yù)防控制中心、海關(guān)出入境檢疫局、衛(wèi)生防疫單位,緝毒系統(tǒng),戒毒中心,檢驗(yàn)檢疫單位、生化企業(yè)、科研院所、醫(yī)療機(jī)構(gòu)等機(jī)構(gòu)與行業(yè)提供*、高品質(zhì)的產(chǎn)品服務(wù)。此外,本公司還開展食品、衛(wèi)生、環(huán)境、藥品等多方面的第三方檢測服務(wù)。)
廣州健侖長期供應(yīng)各種ELISA試劑盒,主要代理進(jìn)口和國產(chǎn)品牌的流行病毒ELISA檢測試劑盒。例如:甲乙型流感病毒酶聯(lián)免疫法檢測試劑盒、黃熱病毒酶聯(lián)免疫法檢測試劑盒、諾如病毒酶聯(lián)免疫法檢測試劑盒、登革病毒酶聯(lián)免疫法檢測試劑盒、基孔肯雅病毒酶聯(lián)免疫法檢測試劑盒、結(jié)核桿菌酶聯(lián)免疫法病毒檢測試劑盒、孢疹病酶聯(lián)免疫法檢測試劑盒、西尼羅河病毒酶聯(lián)免疫法檢測試劑盒、呼吸道合胞病毒酶聯(lián)免疫法檢測試劑盒、冠狀病毒酶聯(lián)免疫法檢測試劑盒等等。蟲媒體染病系列、呼吸道病原體系列、發(fā)熱伴出疹系列、消化道及食源感染系列。
腺病毒IgA、IgG免疫診斷試劑盒
檢驗(yàn)原理
用抗原包被微量板孔,制成固相載體。加患者血清到板孔中,其所含的抗體特異性地與固相載體中現(xiàn)存抗原結(jié)合,形成免疫復(fù)合物。除去多余物質(zhì)后,加入結(jié)合了堿性磷酸酶的IgG、IgA或IgM抗體,使之與上述免疫復(fù)合物反應(yīng)。洗板,除去多余的結(jié)合物,加入底物(對(duì)硝基苯磷酸鹽)。其與酶結(jié)合的免疫復(fù)合物反應(yīng),產(chǎn)生有顏色產(chǎn)物,顏色強(qiáng)度與特異性抗體含量成正比。
產(chǎn)品規(guī)格:96T/盒
存儲(chǔ)條件:4-8℃
我司同時(shí)還提供、美國FOCUS、西班牙DIA、美國trinity等試劑盒:
麻疹、風(fēng)疹、甲流 、乙流、單皰疹1型、單皰疹2型、百日咳、百日咳毒素、腮腺炎、帶狀皰疹、單純皰疹、HSV1型特異性、巨細(xì)胞-特異、風(fēng)疹-特異、弓形蟲-特異、棘球?qū)?、嗜肺軍團(tuán)菌、破傷風(fēng)、蜱傳腦炎、幽門螺旋桿菌、白色念珠菌、博氏疏螺旋體、細(xì)小病毒、鉤端螺旋體、腺病毒、Q熱柯克斯體、煙曲霉菌、??刹《?/span>、EB病毒、衣原體、耶爾森菌、空腸彎曲桿菌、炭疽桿菌、白喉、腸道病毒、柯薩奇病毒、肺炎衣原體、沙眼衣原體、土拉弗朗西斯菌、漢坦病毒、類風(fēng)濕因子、呼吸道合胞病毒、單純皰疹病毒質(zhì)控品、巨細(xì)胞質(zhì)控品、弓形蟲質(zhì)控品、風(fēng)疹麻疹質(zhì)控品、等試劑盒以。
我司還提供其它進(jìn)口或國產(chǎn)試劑盒:登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測、食品安全檢測等試劑盒以及日本生研細(xì)菌分型診斷血清、德國SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。
想了解更多的產(chǎn)品及服務(wù)請掃描下方二維碼:
【公司名稱】 廣州健侖生物科技有限公司
【市場部】 楊永漢
【】
【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103
細(xì)胞
尤其是近年來,隨著引物與探針的設(shè)計(jì)更精確、多通道熒光PCR儀
的開發(fā)與廣泛使用,多重?zé)晒舛縋CR技術(shù)日臻成熟,并以其高通
量、低成本、高效率等優(yōu)點(diǎn)而廣泛應(yīng)用于病毒、細(xì)菌、真菌等多
種病原體的快速檢測,成為應(yīng)用的熱點(diǎn).
基因芯片
與PCR方法相比,基因芯片技術(shù)能同時(shí)獲得更多病原學(xué)、生物學(xué)方
面的信息,從而更為全面地分析、掌握病原微生物的特征。Vora
等[12]運(yùn)用基因芯片技術(shù)對(duì)多種致病性弧菌的毒力、毒素、耐藥
基因及潛在的毒力基因進(jìn)行全面分析,對(duì)掌握這些細(xì)菌的致病性
及進(jìn)行有效預(yù)防、控制等具有重要意義。但基因芯片成本較高,
距離推廣應(yīng)用尚需時(shí)間等待[2] 。
癥狀
人類在自然情況下是霍亂弧菌的*易感者,主要通過污染的水
源或飲食物經(jīng)口傳染。在一定條件下,霍亂弧菌進(jìn)入小腸后,依
靠鞭毛的運(yùn)動(dòng),穿過粘膜表面的粘液層,可能藉菌毛作用粘附于
腸壁上皮細(xì)胞上,在腸粘膜表面迅速繁殖,經(jīng)過短暫的潛伏期后
便急驟發(fā)病。該菌不侵入腸上皮細(xì)胞和腸腺,也不侵入血流,僅
在局部繁殖和產(chǎn)生霍亂腸毒素,此毒素作用于粘膜上皮細(xì)胞與腸
腺使腸液過度分泌,從而患者出現(xiàn)上吐下瀉,瀉出物呈“米泔水
樣”并含大量弧菌,此為本病典型的特征。
霍亂腸毒素本質(zhì)是蛋白質(zhì),不耐熱,56℃經(jīng)30分鐘,即可破壞其
活性。對(duì)蛋白酶敏感而對(duì)胰蛋白酶抵抗。該毒素屬外毒素,具有
很強(qiáng)的抗原性?,F(xiàn)已能將該毒素高度精制成晶狀,仍保持*的
生物學(xué)活性。
霍亂腸毒素致病機(jī)理如下:毒素由A和B兩個(gè)亞單位組成,A亞單位
又分為A1和A2兩個(gè)肽鏈,兩者依靠二硫鏈連接。A亞單位為毒性單
位,其中A1肽鏈具有酶活性,A2肽鏈與B亞單位結(jié)合參與受體介導(dǎo)
的內(nèi)吞作用中的轉(zhuǎn)位作用。B亞單位為結(jié)合單位,能特異地識(shí)別腸
上皮細(xì)胞上的受體。1個(gè)毒素分子由一個(gè)A亞單位和4℃6個(gè)B亞單位
組成多聚體。
Especially in recent years, with the design of primers and probes more accurate, multi-channel fluorescence PCR instrument
The development and widespread use of multiplex fluorescent quantitative PCR technologies are becoming more mature and their high-pass
Volume, low cost, high efficiency and other advantages and widely used in viruses, bacteria, fungi and more
The rapid detection of pathogens, become a hot spot.
Gene chip
Compared with the PCR method, gene chip technology can get more etiology, biology side
Surface information, so as to more fully analyze and master the characteristics of pathogenic microorganisms. Vora
[12] using gene chip technology for a variety of pathogenic Vibrio virulence, toxins, resistance
Genes and potential virulence genes are thoroughly analyzed to understand the pathogenicity of these bacteria
And effective prevention, control and other important. However, the high cost of gene chips,
Distance application still need time to wait [2].
symptom
Humans are the only susceptible to Vibrio cholerae in natural conditions, primarily through contaminated water
Source or food contaminated. Under certain conditions, Vibrio cholera into the small intestine, according to
By flagellar movement, mucous membrane through the mucosal surface, may be attached to the role of pili
Intestinal wall epithelial cells, the rapid proliferation of intestinal mucosal surface, after a short period of incubation
It is a sudden onset. The bacteria do not invade intestinal epithelial cells and enteric glands, nor invasion of blood flow, only
In the local reproduction and produce cholera enterotoxin, this toxin in mucosal epithelial cells and intestine
Gland to make excessive secretion of intestinal fluid, which appears on the patient diarrhea, diarrhea was "rice water
Like "and contains a large number of Vibrio, this is a typical feature of the disease.
Cholera enterotoxin is a protein in nature, not heat, 56 ℃ by 30 minutes, you can destroy it
active. Protease sensitive to trypsin resistance. The toxin is an exotoxin that has
Strong antigenicity. The toxin is now highly refined into a crystalline form and remains extremely strong
Biological activity.
The pathogenesis of cholera enterotoxin is as follows: toxin consists of two subunits A and B, A subunit
Divided into two A1 and A2 peptide chain, the two rely on disulfide link. A subunit is toxic
Of which A1 peptide chain has enzymatic activity, A2 peptide chain and B subunit binding receptor-mediated
The role of translocation in endocytosis. B subunit for the binding unit, can specifically identify the intestine
Receptors on epithelial cells. One toxin molecule consists of one A subunit and four B subunits at 4 ° C
Composition of multimers.